Prof. Dr. Marco Durante is Director of the Biophysics Department at GSI Helmholtz Center for Heavy Ion Research (Darmstadt, Germany) and Full Professor of Physics at the Technical University of Darmstadt. He got his Ph.D. in Physics in 1992 at the University Federico II in Italy, and has dedicated his research efforts to the biophysics of high-energy charged particles, with applications in cancer therapy and space radiation protection. He is generally recognized as world leader in the field of particle radiobiology and medical physics and is co-author of over 400 papers in peer-reviewed scientific journals (h-index=55) and one patent on proton therapy. He is currently chair of the ESA Topical Team on Space Radiation and vice-chair of the Particle Therapy Co-Operative Group (PTCOG). He was President of the International Association for Radiation Research (IARR) from 2011-15. Prof. Durante has been awarded several prizes for his contributions to charged particle biophysics, including the 2004 Galileo Galilei Award in Medical Physics, the 60th Timofeeff-Ressovsky medal by the Russian Academy of Sciences, the 8th Warren K. Sinclair Award of the US National Academy of Sciences, the 2013 IBA-Europhysics Award for Applied Nuclear Science and Nuclear Methods in Medicine (European Physics Society), the 2013 Bacq & Alexander award of the European Radiation Research Society (ERRS), and the 2020 Failla award of the Radiation research Society (RRS). He is recipient of an ERC Advanced Grant in 2020 on particle therapy.

Born in Rome, February 6, 1972. Researcher, permanent position at INFN (Istituto Nazionale di Fisica Nucleare), Sezione di Roma Tre (Italy). PhD in Physics. Research activity @ INFN: 2022-: FLASH Radiotherapy with hIgh Dose-rate particle beAms (FRIDA) - Mechanistic modeling of the FLASH effect with electron and proton beams and their validation. 2021-: MICROdosimetry-based Biological Effectiveness assessment in Ion Therapy (MICROBE-IT) - Coordinator of the working package (WP) for the development and validation of microdosimetric models. 2018-2022: Nuclear process-driven Enhancement of Proton Therapy UNravEled (NEPTUNE) - Coordinator of the WP for the modeling and interpretation of the proton-boron capture therapy. 2015-2019: MoVe-IT - Modeling the impact of target nuclei fragmentation, oxygenation, and intra-tumor heterogeneity in ion beam therapy (IBT). 2014-2015: Nano-Amplified Targeted Therapy (NaTT) - Modeling the biological impact of gold nanoparticles in radiotherapy. 2012-2015: Research and development in hadrontherapy (RDH) and Innovation and Research in Particle Therapy (IRPT) - Coordinator of the WP for the study of advanced treatment planning systems (TPS) for IBT. 2010-2012: Implementation and clinical validation of a TPS for IBT collaboration with Ion Beam Application (IBA).

Dr. Bjorn Baselet studied biomedical sciences at University of Hasselt in Diepenbeek, Belgium. After obtaining his master degree, he performed a PhD at Unversité catholique de Louvain in the field of ionizing radiation-related cardiovascular disease. Currently, he is a senior researcher in the Radiobiology group at the Belgian Nuclear Research Centre (SCK CEN). His research interests lie in the field of space biology, looking into the adverse effects of space stressors such as cosmic radiation exposure on normal tissues with a special emphasis on the immunological and cardiovascular system. Besides his research activities, he is a dedicated mentor of undergrad and PhD students. Furthermore, he is a member of the working group on ionizing radiation at the Belgian High Health Council and received the 2020 MELODI award for his work on radiation-induced cardiovascular disease and immune dysfunction.

Present position 2008- Department of Medical Radiation Physics, Lund University, 221 00 Lund, Sweden Professor of Medical Radiation Physics (2012- ) Director of Studies, Medical Physics Master Program (2012- ) Deputy Head of Department (2013- ) Education 2001 Docent (Associate Professor), Lund University 1999 Certified Medical Physicist, Swedish National Board of Health and Welfare 1995 Ph.D. in Medical Radiation Physics, Lund University 1990 M.Sc. in Radiation Physics, Lund University Previous positions 2003-2008 Head of Radiotherapy Physics, Lund University Hospital 1990-2003 Medical Physicist, Lund University Hospital 1998-2001 Research Assistant, Department of Medical Radiation Physics, Lund University 1997-1998 Visiting Lecturer, Department of Radiation Oncology, University of Pennsylvania Philadelphia, USA 1994-1995 Visiting Senior Research Associate and Clinical Physicist, Department of Radiation Oncology, Brown University, Providence, USA 1990 Medical Physicist, Department of Radiotherapy, Denmark State Hospital, Copenhagen

Matteo Cerri, M.D., Ph.D is an Associate Professor of Physiology at the Department of Biomedical and Neuromotor Sciences of the University of Bologna, associated to the Istituto Nazionale di Fisica Nucleare (INFN), affiliated to the Italian Institute of Technology (IIT), member of the Topical Team Hibernation of the European Space Agency (ESA), of the Roadmap table of Integrative Physiology for the Italian Space Agency (ASI), and in the national board of the Italian Society for Neuroethics (SINe). His research focuses on the neurobiology of hibernation; he was the first to show that it is possible to induce a state mimicking natural hibernation in non-hibernating animals. Currently, he is investigating the mechanism that enhances radiation resistance in hibernators, in the attempt to unravel the molecular mechanism at the base of hibernation-induced radioprotection.

Graduated in Biological Sciences at the University of Pavia, Angelica Facoetti holds a PhD in Cell Biology. First as a post-PhD and then as a full-time researcher, she worked at the Department of Nuclear Physics of the University of Pavia where she carried out in collaboration with the Department of Biology research activities on the cellular effects of ionising radiation. In 2006 she obtained the European Master Degree in Radiation Biology at the University College of London and subsequently the title of Specialization in Clinical Pathology at the Faculty of Medicine and Surgery of the University of Pavia. Her experimental research activity, is focused on the different aspects of cell biology applied to medicine and physics, focusing on the study of underlying mechanisms involved in the effects of various types of ionizing radiations, on tumor and normal cells. She is adjunct professor of Applied Biology at the University of Milan for the School of Specialization in Medical Physics and of Biology, Anatomy and Physiology for the master's degree in Physical Sciences at the University of Pavia. Since 2010 she is responsible for the radiobiological experimental activities at the National Center for Oncological Hadrontherapy (CNAO) of Pavia.

Dariusz Leszczynski, PhD, DSc, Associate Professor of Biochemistry, University of Helsinki, Finland and Chief Editor of specialty ‘Radiation and Health’ at ‘Frontiers in Public Health’, Lausanne, Switzerland. Holds doctorates, in molecular biology (DSc) and biochemistry (PhD), from Jagiellonian University, Krakow, Poland, and from Helsinki University, Finland, respectively. For nearly 22 years (1992-2013) worked at the Finnish Radiation and Nuclear Safety Authority with responsibility for research on biological and health effects of non-ionizing radiation. During the years 2003-2007 was Head of Radiation Biology Laboratory and from 2000 to 2013 Research Professor. Held several visiting appointments: 1997-1999 Assistant Professor at the Harvard Medical School, 2006-2009 - Guangbiao Professor at the Zhejiang University School of Medicine, Hangzhou, China and 2012-2013 Visiting Professor at the Swinburne University of Technology, Melbourne, Australia. An internationally recognized expert in the field of biological and health effects of radiation emitted by wireless communication devices. In this capacity testified in 2009 before the US Senate Committee, in 2015 before the Committee of the Canadian House of Commons and in 2014 advised the Minister of Health of India. In 2011 was one of the 30 experts invited by the International Agency for Research on Cancer who classified cell phone radiation as possibly carcinogenic to humans. Full CV available here: BRHP – Between a Rock and a Hard Place.

Dr Francesco Romano is Researcher at the Italian National Institute for Nuclear Physics (INFN). His expertise is on radiation dosimetry and Monte Carlo simulations for medical applications. He received from University of Catania (Italy) his PhD in Physics in 2010 and his Medical Physics Certification in 2015. He has been working for about ten years at the INFN Southern Laboratory in Catania, coordinating the research activities of two research beam lines, respectively dedicated to proton and ion therapy experimental investigations, also supporting the User's experiments. He was also responsible for the design and realization of the in-air final section of a laser-driven proton beam line for medical applications and the installed dosimetric systems. He moved in 2017 to the United Kingdom, working for almost three years as a Senior Researcher at the National Physical Laboratory in London, which is the UK National Metrology Institute. He have been working here on novel dosimetry developments for proton therapy and FLASH radiotherapy. He came back to Italy three years later working at INFN Catania Division, where he is currently carrying on his research activity on ion beam microdosimetry and dosimetry for hadron therapy and FLASH radiotherapy. He is Honorary Lecturer at the Queen's University of Belfast and University of Surrey in the UK. He is member of the International Geant4 Collaboration and of the Editorial Board of the Applied Physics Journal. He is Reviewer for different Journals in the Medical Physics field and member of the Scientific Committee of several Conferences and International Schools. He is among the proponents of the "UHDpulse" EMPIR joint research project, for dosimetry of ultra-high pulse dose rate beams, and of the INFN FRIDA project for FLASH radiotherapy.

Emanuele Scifoni is "Primo Ricercatore" (Senior Research Scientist) at TIFPA, the Trento Institute for Fundamental Physics and Applications, of the National Institute for Nuclear Physics (INFN, Italy). He got his PhD in theoretical chemical physics in Genoa. He then focused his research interests in radiation biophysical modelling of ion beams for particle therapy. In 2010 he joined the Biophysics department at GSI, Darmstadt, where he contributed substantially to the new developments in the research treatment planning code TRiP98, including new ions, multiple ions optimization and the kill painting method for hypoxic tumors, as well as to to the track structure code TRAX, including the design of its chemical stage extension TRAX-CHEM. He finally moved to Trento in 2016 where he also contributed to the setup of the Trento Proton Beam Experimental Facility and to the establishment of the BiMeR (BioMedical Radiation Physics) research group. He's Principal Investigator and coordinator for the large INFN project Call "MoVe IT"- Modeling and verification for Ion Beam Treatment Planning, and had a leading role in several successful international grants and projects in the field of particle therapy. His most recent research interests focus mainly on biological treatment planning for protons and ion beams, and on elucidating mechanistic features of oxygenation interplay with radiation at the radiation chemistry level, including novel insights in FLASH radiotherapy.

PhD in vascular physiopathology (2006, INSERM, France) and a post-doctoral position on the field of steam cell therapy after high dose accidental ionising radiation (2007-2010). Currently radiobiologist at the institut of radioprotection and nuclear safety in fontenay aux roses, France. For more than 12 years, Teni has led a low-dose radiobiology programm at LRTOX. Her research interest is vascular system within the field of low dose radiation effects with an overaching goal to understanbd mechanisms and long-term effects outcomes on circulatory system such as macrovascular pathologies (atherosclerosis, anevrism) and microvascular defects (neovascularisation process). She also been involved in various international initiatives in low dose radiobiology research (DoReMi, MELODI…). Currently she is a member of UNSCEAR expert group as a contributing author on diseases of circulatory system from radiation exposure.

Dr. Francis A. Cucinotta is Professor of Health Physics at the University of Nevada, Las Vegas (UNLV). He received his doctorate in nuclear physics from Old Dominion University. He worked at NASA from 1990-2013 in several positions including research scientist, radiological health officer for spaceflight, and manager and chief scientist for the Space Radiation Research. He was NASA's manager for the construction and operation of the NASA Space Radiation Lab (NSRL). He developed the NASA quality factors, the astronaut exposure data base of organ doses, and cancer risk estimates for all missions from Mercury to the International Space Station (ISS). He led the ISS biodosimetry program and discovered the association of increased cataract incidence in past space missions. Dr. Cucinotta has published more than 400 peer reviewed journal articles and book chapter (Citations>23,000, h-index=73), and over 80 NASA technical reports in the areas of nuclear and space physics, radiation shielding, DNA damage and repair, biodosimetry, systems biology, and cancer and central nervous system risk assessment models. He has won research grants from NASA, the Department of Energy (DoE), and the National Cancer Institute (NCI). He earned numerous NASA awards for his efforts, received the Barrick Scholar Award in 2018, and the Harry Reid Award for Scholarship in 2020. Dr. Cucinotta served as president of the Radiation Research Society (RRS) in 2014 and received the RRS Failla Award in 2018.

Thomas Friedrich is a senior researcher at GSI biophysics department in Darmstadt, Germany and a lecturer in physics at Technical University Darmstadt. He received his PhD in the field of quantum chaos in 2007 and brought his experience in modelling complex systems into radiation biophysics since 2008. He conducts research on the mathematical modelling of radiation responses in the experimental and clinical context, in particular after ion irradiation, and on experimental data collections for model validation. Considered endpoints include initial DNA damage, cell survival, normal tissue reactions, radiation induced carcinogenesis and, most recently immunologic endpoints upon radiation exposure. Thomas Friedrich habilitated in physics in 2017 at the Technical University of Darmstadt due to his passion for teaching and gives courses in basic physics and biophysics. He received the Dieter Frankenberg price of the German Society for Biological Radiation Research in 2013 and the Hermann Holthusen Price of the German Society for Radiation Oncology in 2020. He is author of about 70 scientific publications.

Ester Hammond completed her PhD at the School for Cancer Sciences, University of Birmingham (UK) then accepted a post as a postdoctoral fellow within the Molecular Oncology Group at the University of Cambridge School of Clinical Medicine before moving to the USA to join the Department of Radiation Oncology at Stanford University, first as a postdoctoral fellow then a research associate. She moved to Oxford to join the Oxford Institute for Radiation Oncology (OIRO) in 2007 to lead her research group. Ester's work focuses on the biological response to tumour hypoxia and specifically the levels at which significant resistance to radiation is observed.

Jolanta Karpowicz received her Master and Engineering Degree in medical and nuclear electronics and DSc (habilitation) in biomedical engineering from the Warsaw Technical University, and PhD (doctorate) in environmental engineering from the Central Institute for Labour Protection – National Research Institute (CIOP-PIB) (Warszawa, Poland), where she is a researcher, the head of Bioelectromagnetics Department (research unit and laboratory accredited in evaluation of electromagnetic field and calibration of measurement devices). Her research area is the electromagnetic environment and its influence on humans and environmental safety, focused mainly on the workers safety, with long years of attention to MRI safety issues. Her main international activities: author of over 100 international journal and conference research articles; reviewer in journals such as Int. J. Radiobiology, Bioelectromagnetics, IJERPH, JOSE; member of COST Actions, EMF-NET team, URSI, BEMS, EBEA, ICOH, IEEE/ICES. She is a member of Polish Society of Radiation Research (PTBR) and Polish Society of Biomedical Engineering (PTIB affiliated to Int. Federation for Medical and Biological Engineering (IFMBE)) and Standardization Technical Committee collaborating with IEC/CENELEC.

Katalin Lumniczky is a medical doctor with a PhD in radiobiology. She graduated at Semmelweis University, Budapest, Hungary in1993 and received her PhD in 2000. Currently she is the head of the Radiation Medicine Unit, National Public Health Centre, Budapest, Hungary. Her major field of research is the impact of ionizing radiation on the immune system and ionizing radiation-induced non-targeted effects with a focus on the role of extracellular vesicles in mediating radiation-related intercellular communication.

Professor of Radiation Biology, at the Patrick G Johnston Centre for Cancer Research at Queen's University Belfast since 2007. Prior to this, he was Head of the Cell and Molecular Radiation Biology Group at the Gray Cancer Institute in Northwood, London. He received his PhD in Cell Biology and Biochemistry, from the University of Aberdeen, on the mechanisms of action of the chemotherapeutic methotrexate. He joined the Gray Laboratory in 1985 working with Barry Michael, under the directorships of Jack Fowler, Julie Denekamp and Ged Adams. He has developed wide-ranging interests in radiation biology including research on low dose radiation risk, radiation quality, cell and tissue signalling mechanisms. His recent work is developing new biological based models for optimising the temporal and spatial aspects of advanced radiotherapies. A current focus is on the radiobiology of new laser-based approaches to probe extreme ultra-high dose-rate regimes. He is a Past-President of the Radiation Research Society, a previous RRS Michael Fry award recipient and Friedrich Dessauer awardee of the German Radiation Research Societies. He was the 2018 Douglas Lea Lecturer, (Institute of Physics and Engineering in Medicine) and the 2018 Bacq and Alexander awardee from the European Radiation Research Society. He has supervised 52 PhD students and has published over 360 papers (h=62), with over 12,800 citations.

Carmen Villagrasa is the head of the ionising radiation dosimetry laboratory (LDRI) at the French Radiation Protection and Nuclear Security Institute (IRSN). She graduated in Fundamental Physics at the University of Paris Saclay (France) in 2000 and at the university of Valencia, Spain in 2001. She did her PhD thesis at the Commissariat à l'Energie Atomique (CEA, France) in 2003 on spallation reaction and,.after à post-doc at the Forshungzentrum Karlsruhe, (Germany), she joined the IRSN in 2006. She has more than ten years of experience in the study of ionising radiation interaction mechanisms with biological targets (DNA in particular) for the calculation of early biological damages using Monte Carlo methods. The main objective of her research is to improve risk models related to side effects in cancer treatments using radiotherapy. With this pupose, a mechanistical approach is followed aiming to describe the physical and chemical radioinduced processes at the base of the earliest biological damage. Results of this work have allowed IRSN to develop specific skills and research techniques in the field of simulation tools for the evaluation of radiation-induced initial DNA damage based on the use of the Geant4-DNA MC code and different geometrical designs of the DNA molecule. In that frame, she is a member of the Geant4 and the Geant4-DNA collaborations. She is also an active member of EURADOS (WG6, Computational Dosimetry) since 2007, and currently Task leader for the Task on micro- and nanodosimetry.

Andrzej Wojcik obtained his PhD in zoology at the University of Vienna in 1990. The practical work was carried out at the Austrian Nuclear Research Centre on cellular effects of low dose ionising radiation. Thereafter he pursued his postdoc at the Institute of Medical Radiation Biology, lead by prof. Christian Streffer. Six years later he moved to the Department of Radiobiology of the Institute of Nuclear Chemistry and Technology in Warszawa, Poland. In 1999 he founded the Department of Radiobiology and Immunology at the Jan Kochanowski University in Kielce, Poland. After a sabbatical year 2006/2007 spent at the High Flux Reactor of the EU JRC Institute of Energy in Petten, Netherlands, he moved in 2008 to the Stockholm University to lead a radiobiology group and, in 2012, became the head of the Centre for Radiation Protection Research, Department of Molecular Biosciences – the Wenner Gren Institute, Stockholm University. Andrzej Wojcik´s research focuses on the biological effects of low radiation doses and mixed beams of radiation of different LET, mechanisms of radiation-induced chromosomal aberrations, biomarkers of radiation exposure and individual response to radiation. In 2011-2012 he was the president of the European Radiation Research Society and is currently the chair of MELODI. He is also a member of the ICRP Main Commission and one of the three editors-in-chief of the journal Radiation and Environmental Biophysics